IT701: A Quality-Assurance Study of ChEBI

TitleIT701: A Quality-Assurance Study of ChEBI
Publication TypeConference Paper
Year of Publication2016
AuthorsYumak H, Chen L, Halper M, Zheng L, Perl Y, Elhanan G
Conference NameInternational Conference on Biomedical Ontology and BioCreative (ICBO BioCreative 2016)
Date Published11/30/16 Volume 1747
Other NumbersVol-1747|urn:nbn:de:0074-1747-1

Ontologies are important components of many health-information systems. The Chemical Entities of Biological Interest (ChEBI) ontology has become a standard reference for chemicals appearing in biological contexts. As such, assuring the quality of its content is imperative. In fact, ChEBI has a dedicated Web page at which errors and inconsistencies in its concepts can be reported. A study of the correctness of a random sample of ChEBI concepts is carried out. The results show that quite a large number of ChEBI concepts suffer from some kind of problematic modeling. For example, we found that 15.5% of the sample concepts exhibited severe errors of commission, including incorrect hierarchical (is a) and lateral relationships. Errors of omission were also prevalent. The overall results of our quality-assurance (QA) study are presented. Suggestions for enhancing the QA processes in place for ChEBI are discussed.