BT201: Text mining to enable routine personalized cancer therapy

TitleBT201: Text mining to enable routine personalized cancer therapy
Publication TypeConference Paper
Year of Publication2016
AuthorsXu H
Conference NameInternational Conference on Biomedical Ontology and BioCreative (ICBO BioCreative 2016)
Date Published11/30/16 Volume 1747
Other NumbersVol-1747|urn:nbn:de:0074-1747-1

Genomic profiling information is frequently available to oncologists, enabling targeted cancer therapy. Because clinically relevant genomic information is rapidly emerging in narrative data sources such as biomedical literature and clinical trials documents, there is a need for text mining technologies to support targeted therapies. In this talk, we will present two projects about developing text-mining tools to enable personalized cancer therapy, including 1) to identify molecular effects of drugs in biomedical literature, and 2) to create a knowledge base of cancer treatment trials with annotations about genetic alterations. We believe such tools would be valuable for physicians and patients who are seeking information about personalized cancer therapy, thus facilitating their decision making.